Silencing of NLRP3 Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin

<div>NLRP3 is upregulated in DPP-resistant ovarian cancer. (a) The tumor tissues from ovarian cancer patients with DDP resistance or not were collected, and the mRNA level of NLRP3 in tumor tissues was assessed by qRT-PCR. (b) The NLRP3 expression in tumor tissues was assessed using a western blot. (c) The NLRP3 expression in tumor tissues was observed using immunohistochemical staining. (d) The NLRP3 level in A2780 and SKOV3 and the DDP-resistant ovarian cancer cells was assessed, adopting qRT-PCR. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: Silencing of NLRP3 Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin 