Upregulation of Biomarker Limd1 Was Correlated with Immune Infiltration in Doxorubicin-Related Cardiotoxicity

Table 3

Analysis of the 14 hub genes in doxorubicin-induced CMs, fibroblasts, and SMCs.

Gene	Cardiomyocytes		Fibroblasts		Smooth muscle cells
	Log FC	Adj.	Log FC	Adj.	Log FC	Adj.
Limd1	-0.69	0.0024	-0.17	0.872	0.27	0.372
Aox1	0.18	0.265	0.13	0.869	2.48	4.76E-06
Spock2	0.49	0.297	—	—	—	—
Sult1a1	0.3	0.182	0.18	0.922	-1.34	0.063
Ephx1	0.26	0.134	0.7	0.606	1.57	6.04E-10
Pcolce	0.14	0.217	0.05	0.962	0.23	0.362
Evi2a	0.41	0.186	1.45	0.214	-0.09	0.93
Klhdc8a	-0.09	0.591	0.65	0.687	0.45	0.639
Slamf9	0.24	0.536	0.65	0.702	—	—
Col15a1	—	—	0.41	0.805	-0.35	0.527
Cd68	0.047	0.86	—	—	-0.05	0.871
Col6a2	—	—	-0.02	0.979	0.31	0.475
Nrep	0.074	0.755	-1.12	0.308	-2.77	1.10E-06
Mgl2	—	—	—	—	—	—

-represents no result.