LINC01088/miR-22/CDC6 Axis Regulates Prostate Cancer Progression by Activating the PI3K/AKT Pathway

Figure 4

si-LINC01088 suppresses PCa cell growth via the PI3K/AKT pathway. (a) Top 10 KEGG pathway enrichment analysis. (b) Western blot analysis of si-LINC01088-mediated protein levels of CDC6, PI3K, p-PI3K, AKT, and p-AKT. (c) Western blot analysis of si-LINC01088/ov-CDC6-mediated protein levels of CDC6, PI3K, p-PI3K, AKT, and p-AKT. CCK8 analysis of the effect of si-LINC01088/ov-CDC6 co-action on the viability rate of (d) PC3 and (e) LNCAP cells. Transwell analysis of the effect of si-LINC01088/ov-CDC6 coaction on migration and invasion of (f) PC3. .

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