Research Article

A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling

Figure 6

(a) The effect of LMT-28 on RANKL mRNA expression of osteoblasts under LPS and AGEs costimulation. (b, c) The effect of LMT-28 on the expression of RANKL protein and the phosphorylation levels of GP130, JAK2, and STAT3 in osteoblasts under LPS and AGEs costimulation and channel blocker baricitinib (repeat three times; , , ).
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