lncRNA DLX6-AS1 Promotes Myocardial Ischemia-Reperfusion Injury through Mediating the miR-204-5p/FBXW7 Axis

Figure 6

DLX6-AS1 deficiency repressed inflammatory response and cell apoptosis in HR-treated H9c2 cells by regulating miR-204-5p. H9c2 cells were transfected with si-DLX6-AS1 or si-NC and miR-204-5p inhibitor or inh-NC, followed by HR treatment. (a) The expression of MCP-1, IL-6, and IL-1β in the H9c2 cells was detected by qRT-PCR. (b) The expression of Bax and Bcl-2 in the H9c2 cells was assessed by WB. (c) Apoptosis of H9c2 cells was measured through flow cytometry. vs. si-NC + inh-NC; ^## vs. si-NC + miR-204-5p inhibitor; ^&& vs. miR-204-5p inhibitor + si-DLX6-AS1.

(a)

(b)

(c)