Provide an explicit statement of the main objective (s) or question (s) the review addresses
Abstract, line 5
Methods
Eligibility criteria
3
Specify the inclusion and exclusion criteria for the review
Not stated in abstract
Information sources
4
Specify the information sources (e.g., databases and registers) used to identify studies and the date when each was last searched
Abstract, line 6 and 7
Risk of bias
5
Specify the methods used to assess risk of bias in the included studies
Abstract, line 7
Synthesis of results
6
Specify the methods used to present and synthesize results
Abstract, line 6–8
Results
Included studies
7
Give the total number of included studies and participants and summarize relevant characteristics of studies
Abstract, line 8
Synthesis of results
8
Present results for main outcomes, preferably indicating the number of included studies and participants for each. If meta-analysis was done, reports the summary estimate and confidence/credible interval. If comparing groups, indicate the direction of the effects (i.e., which group is favored)
Abstract, line 8–12
Discussion
Limitation of evidence
9
Provide a brief summary of the limitations of the evidence included in the review (e.g., study risk of bias, inconsistency, and imprecision).
Not stated in abstracts
Interpretation
10
Provide a general interpretation of the results and important implications
Abstract, line 13 and 14
Other
Funding
11
Specify the primary source of funding for the review
