Impact of Preoperative Neutrophil to Prealbumin Ratio Index (NPRI) on Short-Term Complications and Long-Term Prognosis in Patients Undergoing Laparoscopic Radical Surgery for Colorectal Cancer
Table 4
Univariate and multivariate analysis of OS in CRC patients after surgery.
Variables
Univariate analysis
Multivariate analysis
HR
95% CI
P
HR
95% CI
P
Gender
0.990
0.645–1.520
0.963
—
—
—
Age
1.025
1.002–1.048
0.036
1.006
0.982–1.031
0.614
BMI
1.023
0.950–1.102
0.546
—
—
—
Preoperative hemoglobin
0.998
0.988–1.008
0.732
—
—
—
Hypertension
1.312
0.818–2.105
0.260
—
—
—
Diabetes
0.993
0.527–1.871
0.982
—
—
—
History of abdominal surgery
1.632
1.004–2.652
0.048
0.519
0.309–0.874
0.014
Intraoperative bleeding
1.287
0.798–2.077
0.301
—
—
—
Intraoperative transfusion
0.895
0.283–2.832
0.850
—
—
—
Surgical duration
1.012
1.001–1.024
0.038
0.998
0.987–1.009
0.696
CEA
1.045
0.663–1.600
0.838
—
—
—
Preventive ostomy
0.690
0.395–1.206
0.193
—
—
—
Tumor maximum diameter
0.484
0.315–0.745
0.001
2.426
1.535–3.835
<0.001
Tumor differentiation grade
2.355
1.533–3.618
<0.001
0.392
0.249–0.618
<0.001
TNM stage
1.598
1.044–2.446
0.031
0.742
0.473–1.164
0.193
NPRI
6.039
3.621–10.072
<0.001
0.212
0.111–0.407
<0.001
NLR
2.654
1.731–4.067
<0.001
0.933
0.568–1.534
0.785
NAR
4.041
2.610–6.256
<0.001
0.701
0.400–1.226
0.213
PAR
2.090
1.255–3.483
0.005
0.921
0.512–1.657
0.784
Indicates the statistical significance of all P values < 0.05.
