Impact of Preoperative Neutrophil to Prealbumin Ratio Index (NPRI) on Short-Term Complications and Long-Term Prognosis in Patients Undergoing Laparoscopic Radical Surgery for Colorectal Cancer
Table 5
Univariate and multivariate analysis of DFS in CRC patients after surgery.
Variables
Univariate analysis
Multivariate analysis
HR
95% CI
P
HR
95% CI
P
Gender
0.827
0.581–1.178
0.294
—
—
—
Age
1.021
1.002–1.041
0.028
1.006
0.986–1.026
0.580
BMI
1.006
0.945–1.070
0.852
—
—
—
Preoperative hemoglobin
0.993
0.985–1.001
0.109
—
—
—
Hypertension
1.552
1.061–2.270
0.023
0.939
0.623–1.415
0.763
Diabetes
0.925
0.539–1.588
0.778
—
—
—
History of abdominal surgery
1.717
1.152–2.559
0.008
0.459
0.299–0.705
<0.001
Intraoperative bleeding
1.330
0.896–1.975
0.157
—
—
—
Intraoperative transfusion
1.034
0.423–2.531
0.941
—
—
—
Surgical duration
1.010
1.000–1.020
0.042
1.004
0.994–1.014
0.445
CEA
0.898
0.630–1.279
0.550
—
—
—
Preventive ostomy
0.821
0.529–1.274
0.379
—
—
—
Tumor maximum diameter
0.278
0.189–0.408
<0.001
4.782
3.162–7.232
<0.001
Tumor differentiation grade
2.546
1.784–3.634
<0.001
0.305
0.207–0.449
<0.001
TNM stage
2.331
1.622–3.349
<0.001
0.397
0.270–0.586
<0.001
NPRI
2.305
1.611–3.298
<0.001
0.552
0.338–0.900
0.017
NLR
1.712
1.198–2.448
0.003
1.060
0.688–1.631
0.792
NAR
2.374
1.665–3.384
<0.001
0.781
0.478–1.275
0.323
PAR
1.404
0.955–2.065
0.084
—
—
—
Indicates the statistical significance of all P values < 0.05.
