Research Article
The Causal Relationship between Plasma Myeloperoxidase Levels and Respiratory Tract Infections: A Bidirectional Mendelian Randomization Study
Table 2
Pleiotropy and heterogeneity test of the bidirectional Mendelian randomization study.
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Horizontal pleiotropy analyses were conducted by MR-Egger regression and MR-PRESSO methods, and the results showed that there is no evidence of horizontal pleiotropy in IVs of infectious diseases (all ). Heterogeneity tests were conducted by MR-Egger regression and IVW with the fixed model, and the results showed that there is no evidence of heterogeneity in IVs of infectious diseases (all ). PRESSO, MR-Pleiotropy RESidual Sum and Outlier; IVW, inverse variance weighted method with the fixed effect model. , MPO-related SNPs from the Folkersen et al. [20] study; MPO#, MPO-related SNPs from INTERVAL study [21]. |