Photoprotective Effects of Epigallocatechin Gallate on Ultraviolet-Induced Zebrafish and Human Skin Fibroblasts Cells

Figure 5

The effects of EGCG on involving photoaging protein expressions. The effects of EGCG on phosphorylation p38 MAPK (a, b), AP-1 (c, d), NF-κB (e, f), TNF-α (g, h), IL-1α (i, j), IL-6 (k, l), and MMP-1 (m, n) expressions in UVR-induced zebrafish larvae (25 μM EGCG) and HSF cells (50 μM EGCG) for 72 hr. The protein bands of c-jun and NF-κB were nuclear extracts of HSFs. The experiments were repeated three times. Data are presented as means ± SD (n = 3). , , and compared with control group. ^&, ^&&, and ^&&& compared with UVR group.

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