Optimization Manufacture of Virus- and Tumor-Specific T Cells

Figure 5

Optimization of antigen-specific CTL manufacture decreases the number of interventions while increasing the cell output. (a) illustrates the level of complexity associated with the generation of antigen-specific CTLs using conventional 24-well plates and the reduced number of interventions required when reproducing the same protocol using the G-Rex. (b) shows how the implementation of the G-Rex device decrease the in vitro culture time when compared with the conventional method.