Advances in Cell Transplantation Therapy for Diseased Myocardium

Table 1

Cell transplantation by intramyocardial injection and vascular infusion in clinical studies.

Cell injection to myocardium
Cell type	×10^6 cells	Function	Remarks
Myoblast	…	↑	Arrhythmogenic potential	[20]
Myoblast	206	No effect	Arrhythmogenic potential	[21]
Myoblast	400–800	No effect	Arrhythmia	[14]
Myoblast	870	…	Arrhythmogenic potential	[22]
Myoblast, BMSC	300, 100	↑		[15]
Vascular infusion
Cell type	×10^6 cells	Function	Remarks
BMSC	~1.5–9	…	Restoration of coronary flow reserve	[12]
BMSC	39	↑		[13]
BMSC	68	No effect		[11]
BMSC	~100–300	↑	Lower mortality	[8]
BMSC	200–400	No effect	Infarct remodelling	[10]
BMSC	56–60 000	↑		[9]

BMSC: bone marrow stem cell.