Ion Channel Activities in Neural Stem Cells of the Neuroepithelium

Table 1

Neuroepithelial-cell-ion channels and their functions.

Type of ion channel	Function of ion channel
Ion channels in the plasma membrane
Gap junction channel	Stabilizing membrane potential by lowering input resistance
Store-operated Ca^2+ entry channel (TRP or Orai)	Replenishing Ca^2+ stores after Ca^2+ release
Epithelial Na^+ channel	Continuous Na^+ influx from ventricular space to generate DC potential
L-type voltage-dependent Ca^2+ channel	Ca^2+ influx by depolarization
BK channel	Repolarizating after depolarization and intracellular [Ca^2+] rise
GABAA receptor channel	Depolarizing in response to GABA
P2X purinoceptor channel	Depolarizing in response to ATP
Ion channels in the nuclear envelope and the endoplasmic reticulum
InsP3 receptor channel	Ca^2+ release by activation of muscarinic acetylcholine receptor, P2Y purinoceptor, and lysophosphatidic acid receptor
BK channel	Counter ion movement for Ca^2+ release to maintain driving force for Ca^2+ release