Extrafollicular Dermal Melanocyte Stem Cells and Melanoma

Table 1

Evidence for the presence of extrafollicular dermal MSCs in human skin and in association with peripheral nerves of other vertebrates.

Source	Origin	MSC marker	Marker type
Human	Dermis	kit (+), trp-1(−), bcl-2 (+)	Cytokine receptor, tyrosinase apoptosis regulator [6]
Human	Dermis	NGFRp75, Oct-4	Nerve growth factor [7–9]
Quail	Schwann cells	ETR-B	Endothelin receptor [29]
Chicken	Spinal ganglia	Melanin	Pigment [31]
Zebrafish	Dermis	trp-1 (−)	Tyrosinase [37–40]
Zebrafish	Nerve	foxd3 and sox10	Transcription factors [41]