(a) RNA profiling of POSTN in human extraembryonic tissues of three individual embryos by RT-qPCR. Gestational age is represented by weeks (w) and days (d). (b) Relative RNA expression of Postn/POSTN in mouse and human amnion samples from different developmental stages. In human amnion POSTN is expressed at very high levels during the first trimester, followed by a significant drop in expression, whilst Postn expression in mouse amnion is stable during gestation. Mouse and human developmental stages are positioned along an arbitrary interval scale. Mouse and human gestation approximates 19.5 days and 38 weeks respectively. Mouse and human developmental stages do not match pairwise. Abbreviations: Am: amnion; Ch: chorion, E: embryonic day; Pl: placenta, UC: umbilical cord, 8–38 w: weeks of gestation.
