|
| Growth factors secreted by CD133+/CD34+ BMMNCs | |
|
| (a) Proangiogenic factors | |
| Angiogenin | |
| Angiopoitien-2 | |
| b-FGF (basic fibroblast growth factor) | |
| PLGF (placenta growth factor) | |
| VEGF-121 (vascular endothelial growth factor-121) | |
| VEGF165 (vascular endothelial growth factor-165) | |
| VEGF-D (vascular endothelial growth factor-D) | |
|
| (b) Proinflammatory factors | |
| I-309 (CCL-1 (C-C motif) ligand-1) | |
| MCP-1 (CCL-2 (C-C motif) ligand-2) | |
| MIP-1a (CCL-4 (C-C motif) ligand-4) | |
| RANTES (CCL-5 (C-C motif) ligand-5) | |
| IL-1ra (interleukin-1 receptor antagonist) | |
| CXCL-16 (C-X-C motif) ligand-16 | |
| MIF (macrophage migration inhibitory factor) | |
| sTNFR-1 (soluble tumor necrosis factor receptor-1) | |
|
| (c) MMPs-TIMPs | |
| MMP-1 (matrix metalloproteinase-1) | |
| MMP-3 (matrix metalloproteinase-3) | |
| MMP-9 (matrix metalloproteinase-9) | |
| MMP-13 (matrix metalloproteinase-13) | |
| TIMP-1 (tissue inhibitor of metalloproteinases-1) | |
| TIMP-2 (tissue inhibitor of metalloproteinases-2) | |
| TIMP-4 (tissue inhibitor of metalloproteinases-4) | |
|
| (d) Neurophilic factors | |
| AGRP (agouti-related protein) | |
| BDNF (brain-derived neurotrophic factor) | |
| CTNF (human ciliary neurotrophic factor) | |
| b-NGF (basic nerve growth factor) | |
| AREG (amphiregulin) | |
| NT-3 (neurotrophin-3) | |
| NT-4 (neurotrophin-4) | |
| Activin A (promotes neural cell differentiation) | |
Prolactin (promotes neurogenesis in maternal and foetal
brains) | |
|
| (e) Morphogenetic proteins | |
| BMP-4 (bone morphogenetic protein-4) | |
| BMP-5 (bone morphogenetic protein-5) | |
| BMP-6 (bone morphogenetic protein-6) | |
| BMP-7 (bone morphogenetic protein-7) | |
|
