Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer

Figure 2

Relative overexpression (expressed as ( of CRC of nontumor)) of (a) OPN, (b) OCT4, (c) SOX2, and (d) Nanog in DLD1-OPN stable clones #1 and #3 and the vector control; the relative number of viable cells (expressed as percentage of viable cells when compared with vehicle treated cells) after 72-hour treatment of (e) 5 μM oxaliplatin and (f) 50 μM 5FU.

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