Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells

Table 1

Summary of references for natural materials in combination with hydroxyapatite.

Source of stem cells	Material used	Results	Study/reference
hMSCs	Collagen/fibronectin/HA	Cells are viable on the scaffold	Antebi et al. 2013/[12]
BMSCs and DPSCs	Fibronectin/collagen/albumin coating for HA versus allographs	↑ cell attachment for allographs coated with albumin	Weszl et al. 2012/[13]
BMSCs, PDL fibroblasts, and HBCs	Gelatin/HA	↑ ALP activity for moderate HA levels	Rungsiyanont et al. 2012/[14]
WJ-MSCs	HA/gellan gum/gelatin	Cells are viable on the scaffold	Barbani et al. 2012/[15]
BMSCs	CS/HA	↑ osteocalcin expression/staining, ↑ ALP expression/staining, ↑ Col1αI expression, ↑ Runx2 expression	Kim et al. 2013/[16]
BMSCs	CS/hyaluronic acid/nHA	↑ ALP activity	Chen et al. 2012/[17]
BMSCs	CS/fibronectin/vitronectin/nHA	↑ calcium deposition, ↑ collagen content, ↑ total protein synthesis	Wang et al. 2014/[18]
hMSCs	CS/PgA/nanoclay	↑ ARZ staining, ↑ ALP activity	Ambre et al. 2013/[19]
BMSs	Silk/HA	↑ collagen I staining, ↑ bone sialoprotein staining, ↑ osteocalcin staining, ↑ calcium deposition	Bhumiratana et al. 2011/[20]