Particle Radiation-Induced Nontargeted Effects in Bone-Marrow-Derived Endothelial Progenitor Cells

Figure 4

Cumulative levels of inflammatory cytokines and chemokines are significantly increased in ¹H-IR conditioned medium. Graphic representation of IR-induced increases in the cumulative concentration (pg/mL) of cytokines, chemokines, and growth factors in CM from 90 cGy ¹H-IR BM-EPCs in vitro at 2, 5, and 24 h after IR for (a) IL-1α, (b) IL-1β, (c) G-CSF, (d) GM-CSF, (e) MCP-1, (f) MIP-1α, (g) SCF, and (h) Rantes. Graphs represent mean ± SEM of the pooled data from 3 independent biological samples/experiments. Statistical significance was assigned when .

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