Review Article
Trophic Factors from Tissue Stem Cells for Renal Regeneration
Table 2
Summary of the adult kidney stem cells.
| | Factor | Trophic effect |
| | HGF | Cell proliferation, anti-inflammation, antifibrosis | | EGF | Mitogenesis (renal proximal tubules), anabolism | | IGF-1 | Mitogenesis (renal proximal tubules) | | bFGF | Antiapoptosis, epithelial condensation, WT-1 upregulation,
cell proliferation, MSC differentiation | | VEGF | Cell proliferation, matrix remodeling, monocyte chemotaxis,
adhesion protein upregulation | | BMP-7 | Antifibrosis, anti-inflammation, antiapoptosis | | PGE2 | Anti-inflammation | | TGF-b | Anti-inflammation | | MVs | Cell proliferation, antiapoptosis, dedifferentiation (renal mature cells) | | microRNAs | Kidney development, homeostasis, and renal disease |
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