What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells?

<div>Comparison of UCX (black bars) and BM-MSCs (grey bars) transcriptome of immunomodulatory genes. (a) Relative gene expression of known MSC and immune response related genes in UCX (derived from 3 different umbilical cords) and BM-MSCs (2 different donors) are represented as mean <svg height="7.56353pt" id="M34" style="vertical-align:-0.3629899pt" version="1.1" viewbox="-0.0498162 -7.20054 8.07242 7.56353" width="8.07242pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M556 297V350H337V548H275V350H56V297H275V85H337V297H556ZM556 -23V30H56V-23H556Z" id="g54-37"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="611" vert-adv-y="611"></glyph.data></g></svg> s.e.m. Unbroken line was positioned on the average negative known markers of MSCs. Genes with relative expression values above this line were considered substantially expressed. (b) Genes where there was a relative expression significantly increased or decreased 20% or more.</div>

Stem Cells International

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Figure 5

Figure 5: What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells? 

Figure 5 | What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells? 