Neural Progenitor Cells Derived from Human Embryonic Stem Cells as an Origin of Dopaminergic Neurons

Figure 2

Differentiation potential of neural progenitor cells derived from human embryonic stem cells. In order to induce terminal differentiation, neural progenitor cells were let to form neurospheres for 7 days. The cells were then replated, immunostained, and found to give rise to several cell types, such as oligodendrocytes (O4), GABAergic neurons (GABA), and dopaminergic neurons (TH). TUJ1-positive neurons (red) and GFAP-positive glial cells were codetected in differentiating culture.