Mesenchymal Stromal Cells and Viral Infection

Figure 1

The proposed double-edge sword effect of using MSCs as a treatment for viral diseases. Several transplant-related complications and viral-associated diseases such as GvHD, low CD4+ numbers, ALI, and chronic hepatitis have been successfully improved by administered MSCs. The susceptibilities of MSCs to each viral infection may occur concurrently after infusion according to several infection evidences in vitro. GvHD, graft-versus-host disease; ALI, acute lung injury; HIV, Human Immunodeficiency Virus; HBV, Hepatitis B Virus; MSCs, Mesenchymal Stromal Cells.