Multipotent Mesenchymal Stromal Cells: Possible Culprits in Solid Tumors?

Table 2

(Positive) Phenotypic markers and features for both MSCs and TAFs based on [15, 60–63]. Markers for which presence in both TAFs and MSCs has been demonstrated are shown in the middle while markers which have only been demonstrated in either one of the cell types are presented in the left or right column.

MSCs	Tumor associated fibroblasts
Minimal criteria for the definition of MSCs
CD73, CD90, CD105
(according to ISCT)
Extracellular matrix proteins
tenascin-c, thrombospondin-1, periostin
Adhesion molecules/lineage markers
HCAM, VCAM-1, MCAM, LCAM, integrin-β1,
Growth
factors/hormones
SDF-1, NPPB, FGF, VEGF, FGFR3
Immunological markers
HLA-ABC
Various other markers	Activation marker
CD44, CD271, CD71, CD106, CD146, MSCA-1	FAP