Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes

Figure 5

Adult donor acd-MSCs accelerated wound closure kinetics. Murine excisional wound model in which wounds were treated with (a) 1x dose and (b) 6x dose of acd-MSCs from young, adult, and old donors’ BM-MSCs or Alpha-MEM medium (vehicle). Representative photographs of C57BL/6 wounds before treatment or 4, 8, and 12 days afterwards. Measurement of wound size at different times. Data are mean ± SEM (vehicle ; 1x dose of acd-MSCs from BM-MSCs from young (), adult (), and old donors () and 6x dose of acd-MSCs from MSCs from young (), adult (), and old donors ()).   : young, adult, and old versus vehicle.

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