TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis

Figure 2

Influence of preexposure of HPCs to TGF-β1 for different periods of time on the morphology of HPCs. Schematic of the experimental procedure (a). After exposure to TGF-β1 for 12 h, the HPCs were cocultured with HSCs. The HSCs lost their typical spindle shape, while the other groups did not experience any morphological changes (b).

(a)

(b)