Mesenchymal Stem Cell Treatment for Steroid Refractory Graft-versus-Host Disease in Children: A Pilot and First Study from Turkey

Table 2

Characteristics of GVHD and response to MSC therapy.

Patients	Skin/GI/liver; (stages)	aGVHD (grade)	Response	Follow-up	Cause of death
1	2/4/0	IV	CR	Alive with extensive chronic GVHD
2	2/2/2	III	CR	Death	Bacterial infection
3	2/4/0	IV	NR	Death	Extensive chronic GVHD
4	4/3/0	IV	CR	Alive, no GVHD
5	3/3/0	III	CR	Death	Extensive chronic GVHD + infection
6	4/4/0	IV	CR	Death	Leukemia relapse
7	2/4/4	IV	NR	Death	aGVHD + infection
8	4/2/2	IV	NR	Death	aGVHD + infection
9	3/4/3	IV	CR	Alive, no GVHD
10	4/4/3	IV	CR	Alive, no GVHD
11	4/4/3	IV	PR	Death	aGVHD + infection + VOD
12	4/4/1	IV	CR	Alive with limited chronic GVHD
13	3/4/2	IV	PR	Alive, no GVHD
14	4/0/0	IV	PR	Alive with limited chronic GVHD
15	4/4/0	IV	CR	Alive with limited chronic GVHD
16	0/4/0	IV	CR	Alive, no GVHD
17	4/2/4	IV	PR	Death	aGVHD + infection
18	4/4/4	IV	NR	Death	aGVHD
19	4/0/0	III	CR	Alive with extensive chronic GVHD
20	4/4/3	IV	NR	Death	aGVHD
21	4/4/0	IV	NR	Death	aGVHD + infection
22	4/4/0	IV	CR	Alive with extensive chronic GVHD
23	4/4/0	IV	CR	Alive, no GVHD
24	4/4/3	IV	PR	Alive, no GVHD
25	3/3/4	IV	NR	Death	aGVHD + infection + VOD
26	3/4/0	IV	PR	Death	aGVHD + infection
27	2/4/0	IV	CR	Alive with extensive chronic GVHD
28	4/0/0	III	CR	Alive, no GVHD
29	2/4/0	IV	CR	Alive, no GVHD
30	4/0/0	III	CR	Alive, no GVHD
31	3/4/4	IV	NR	Death	aGVHD
32	4/4/0	IV	PR	Alive, with aGVHD
33	2/4/0	IV	CR	Alive, no GVHD

GVHD = graft-versus-host disease; GI = gastrointestinal; CR = complete response; PR = partial response; NR = no response; VOD = venoocclusive disease.