Mesenchymal Stem Cells Derived from Human Exocrine Pancreas Spontaneously Express Pancreas Progenitor-Cell Markers in a Cell-Passage-Dependent Manner

Figure 6

Correlations between transcription factor expressions in hpMSCs and in pancreas progenitor cells. Human exocrine pancreas tissue-derived hpMSCs express Pdx1, Nkx2.2, Nkx6.1, and P48 at levels comparable to those in pancreatic progenitor cells. hpMSCs also specifically express other factors, including Ngn3, Isl1, Pax6, and MafA, associated with pancreas-endocrine developmental lineage.