|
Functional category | Gene symbol | Biological process | Accession number | Absolute fold change |
|
Biomineral tissue development | PHEX | Bone and dentin mineralization | NM_000444 | 160.01 |
DMP1 | Bone and dentin mineralization | NM_004407 | 99.20 |
CALB1 | Hydroxyapatite formation | NM_004929 | 98.07 |
MMP20 | Regulation of enamel mineralization, proteolysis | NM_004771 | 85.26 |
AMBN | Bone mineralization, odontogenesis of dentine-containing tooth | NM_016519 | 65.69 |
DSPP | Odontogenesis of dentine-containing tooth | NM_014208 | 41.26 |
ALPL | Biomineral tissue development | NM_000478 | 14.83 |
DLX1 | Odontogenesis of dentine-containing tooth | NM_178120 | 9.55 |
LHX8 | Odontogenesis of dentine-containing tooth | NM_001001933 | 7.56 |
CA2 | Odontogenesis of dentine-containing tooth | NM_000067 | 7.07 |
RUNX2 | Ossification, osteoblast differentiation | NM_001024630 | 6.53 |
LEF1 | Odontogenesis of dentine-containing tooth | NM_016269 | 6.24 |
PAX9 | Tooth development | NM_006194 | 5.79 |
MSX1 | Odontogenesis, craniofacial development | NM_002448 | 4.04 |
WNT10A | Regulation of odontogenesis of dentine-containing tooth | NM_025216 | 3.87 |
|
Developmental process | DLX5 | Osteoblast differentiation | NM_005221 | 30.01 |
DLX3 | Multicellular organismal development | NM_005220 | 26.13 |
ADAM22 | Proteolysis, central nervous system development | NM_021723 | 25.00 |
NES | Central nervous system development | NM_006617 | 15.67 |
BMP7 | Ossification, organ morphogenesis | NM_001719 | 15.60 |
BMPR1B | Skeletal system development, cartilage condensation | NM_001203 | 13.53 |
MSX2 | Skeletal system development, osteoblast differentiation | NM_002449 | 9.32 |
COL11A2 | Skeletal system morphogenesis, cartilage development, palate development | NM_001163771 | 8.55 |
BMP5 | Skeletal system development, ossification | NM_021073 | 6.08 |
TBX3 | Blood vessel development, in utero embryonic development | NM_016569 | 5.93 |
MBP | Central nervous system development, myelination | NM_001025101 | 4.95 |
DLX6 | Multicellular organismal development, nervous system development | NM_005222 | 4.12 |
NRCAM | Axonogenesis, central nervous system development | NM_001193582 | 4.09 |
SNAI1 | Osteoblast differentiation, mesoderm formation | NM_005985 | 3.78 |
HLF | Multicellular organismal development, rhythmic process | NM_002126 | 3.23 |
BMP2 | Development of bone and cartilage | NM_001200 | 2.11 |
|
Physiological process | TF | Controlling iron concentrations, erythropoiesis | NM_001063 | 153.98 |
SCN7A | Sodium ion transport, muscle contraction | NM_002976 | 82.36 |
APOD | Lipid metabolic process | NM_001647 | 41.22 |
PLAT | Response to hypoxia, blood coagulation | NM_000930 | 10.20 |
CD52 | Elevation of cytosolic calcium ion concentration | NM_001803 | 4.29 |
CYGB | Response to oxidative stress, oxygen transport | NM_134268 | 3.98 |
MYOT | Muscle contraction | NM_006790 | 3.26 |
|
Signal transduction and regulation | WIF1 | Wnt receptor signaling pathway | NM_007191 | 70.19 |
PTN | Transmembrane receptor protein signaling pathway | NM_002825 | 38.17 |
WNT5A | Oncogenesis, embryogenesis | NM_003392 | 13.68 |
NCAM1 | Neurite outgrowth, synaptic plasticity | NM_181351 | 7.87 |
NCAM2 | Neurite outgrowth, synaptic plasticity | NM_004540 | 7.38 |
RASGRF2 | Induction of apoptosis by extracellular signals | NM_006909 | 6.88 |
CHN1 | Signal transduction | NM_001822 | 6.56 |
MET | Cell surface receptor linked signaling pathway | NM_001127500 | 3.01 |
|
Cell regulation and proliferation | SCIN | Negative regulation of cell proliferation | NM_001112706 | 58.65 |
RELN | Cell morphogenesis involved in differentiation | NM_005045 | 49.12 |
NES | Structural organization of the cell | NM_006617 | 15.67 |
MEGF10 | Phagocytosis | NM_032446 | 9.89 |
EPCAM | Positive regulation of cell proliferation | NM_002354 | 8.79 |
PDGFD | Positive regulation of cell division | NM_025208 | 5.43 |
CLU | Cell death, positive regulation of cell proliferation | NM_001831 | 5.19 |
VEGFC | Angiogenesis, positive regulation of neuroblast proliferation | NM_005429 | 3.74 |
MSI2 | Stem cell development | NM_138962 | 3.55 |
DBC1 | Cell cycle arrest, cell death | NM_014618 | 3.32 |
TGFB1 | Cell growth, cell proliferation, cell differentiation and apoptosis | NM_000660 | 3.14 |
IGFBP6 | Regulation of cell growth | NM_002178 | 3.07 |
|
Cytokine, chemokine, and immune response | IGJ | Immune response | NM_144646 | 22.65 |
IGHD | Immune response | BC021276 | 11.30 |
CXCL14 | Chemotaxis, immune response, inhibiting angiogenesis | NM_004887 | 8.74 |
SELE | Leukocyte migration involved in inflammatory response | NM_000450 | 5.82 |
MX1 | Induction of apoptosis, defense response, response to virus | NM_002462 | 5.24 |
IFI44 | Response to virus | NM_006417 | 5.05 |
CX3CL1 | Chemotaxis, defense response, immune response | NM_002996 | 3.60 |
CFI | Innate immune response | NM_000204 | 3.17 |
|