Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria

Figure 5

UC-MSCs inhibited respiratory mitochondrial accumulation in T cells from SLE patients. PBMCs from SLE patients were activated with anti-CD3/CD28 antibodies and cultured with or without mesenchymal stem cells (UC-MSCs) for 72 h. All experiments were performed in triplicate. (a–c) UC-MSCs inhibited respiratory mitochondrial accumulation in activated CD3+T, CD4+T, and CD8+T cells (). ns, not significant;  .

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