Dynamic Tracking of Injected Mesenchymal Stem Cells after Myocardial Infarction in Rats: A Serial 7T MRI Study

Figure 1

Dual-labeled mesenchymal stem cells (MSCs). (a) Phase contrast images showed almost 99% of the cells labeled with MPIO (original magnification ×100). (b) The iron particles gathered in the cytoplasm and perinuclear area (original magnification ×400). (c) Iron staining demonstrated high MPIO labeling efficiency (>98%) represented as numerous blue granules in the cytoplasm (original magnification ×100). (d)–(f) The green fluorescence of the MPIOs was clearly detected in the cytoplasm (d and f) and the red CM-DiI in the membrane of MSCs (e and f), original magnification ×400.

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