Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro

Figure 3

Cellular organelle state and ROS level in ASCs after coculture with PHA-stimulated PBMCs versus ASCs in monoculture. Transmembrane mitochondrial potential (a), lysosome activity (b), endoplasmic reticulum activity (c), and ROS production (d). Significant difference between monocultured and cocultured ASCs at 20% O₂ (). Significant difference between monocultured and cocultured ASCs at 5% O₂ ().

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