Tissue Inhibitor of Matrix Metalloproteinases-1 Knockdown Suppresses the Proliferation of Human Adipose-Derived Stem Cells

Figure 5

TIMP-1 knockdown blocked cell cycle progression. Cells were stained with propidium iodide and cell cycle distribution was then analyzed using flow cytometry 72 h after infection. (a) Representative images of cell cycle distribution in parental, mock-shRNA, and shTIMP-1 ADSCs. (b) The histogram was the statistical data from three independent experimental replicates. versus the mock-shRNA groups.

(a)

(b)