tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis

Figure 1

In vitro studies for quantification of angiogenesis ability in (a–d) illustrating the results of aortic ring culture in wild-type (WT) (a, c) and MMP-9^−/− (b, d) mice, respectively. (e) Analytical result of mean distance of sprouts. (f) Analytical result of mean sprout area. indicates between MMP9^−/− group and WT group. for each group.

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