Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy

Figure 4

The effect of CDCs on cardiac function. In untreated controls, regional and global function assessed by echocardiography were severely reduced. After 4 weeks, CDCs significantly improved LAD and remote wall thickening, producing an improvement in LV ejection fraction.