Research Article

Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy

Table 3

The effects of CDCs on echocardiographic measurements.

LAD WT (%)Remote WT (%)FS (%)EF (%)

Untreated animals
 Initial620 ± 458 ± 418 ± 139 ± 2
 Final13 ± 647 ± 813 ± 232 ± 3
CDCs
 Initial516 ± 651 ± 513 ± 129 ± 3
 Final36 ± 699 ± 1021 ± 245 ± 4

Values are mean ± SEM; versus initial; versus untreated animals; LAD: left anterior descending coronary artery; WT: wall thickening; FS: fractional shortening; and EF: ejection fraction.