Umbilical Cord Tissue-Derived Mesenchymal Stem Cells Induce T Lymphocyte Apoptosis and Cell Cycle Arrest by Expression of Indoleamine 2, 3-Dioxygenase

Figure 6

1-MT reverses T lymphocytes cell cycle arrest induced by hUC-MSCs. Cultured T lymphocytes were stimulated for 120 h with PHA in the presence or absence of hUC-MSCs and 1-MT. At harvest, the DNA content of the cells was measured by PI staining using flow cytometry. (a) The FACS plots were representative of one of three experiments. (b) The results of three independent experiments were averaged. Bars represent the SD. .

(a)

(b)