MRI-Based Assessment of Intralesional Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in a Model of Equine Tendonitis

Figure 9

Transverse MRI of SDFT and quantification of low MRI signal as measured on 8-bit, grayscale images. (a) Graph showing summation of low signal intensity pixels before and after subtraction of DDFT and SDFT from transverse images. (b) Summation of low signal intensity pixels in the subcutaneous and surrounding soft tissues in all 6 subjects with a magnified view of the x-axis displayed on the right. (c) TRUFI images demonstrating substantial efflux of cells into the paratendinous and surrounding tissues. Arrows indicate hypointense areas of MRI signal representative of SPIO-treated cells. Dotted lines estimate the boundaries of the SDFT and DDFT.

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