Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats

Figure 3

rASC-based hydrogel accelerating muscle regeneration. (a) H&E staining of TA muscle during repair and regeneration at 1 w, 2 w, 4 w, and 8 w post injury. Scale bar = 100 μm. (b) Sirius Red staining at 5 d post injury and collagen analyzed. Scale bar = 100 μm. (c) Masson trichrome staining of TA muscle at 8 w post injury and collagen analyzed. Scale bar = 200 μm. (d) Laser Doppler perfusion images at 2 w post injury. Images above were representatives of at least three independent experiments. Data were mean ± SEM of three independent experiments. versus hydrogel group.

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