Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury

Figure 1

Development of animal models of spinal cord injury. (Upper illustration) methods for inducing spinal cord injury via surgical incision include transection and hemisection, both of which can be accomplished using a surgical knife (left). Hind limb paralysis following thoracic spinal cord injury in rats (right). (Lower table) animal models categorized by lesion method (left), the resulting primary pathology (middle), and final result of affected motor neurons (right).