CD60b: Enriching Neural Stem/Progenitor Cells from Rat Development into Adulthood

Figure 1

CD60b expression decreases throughout cortical development. Confocal photomicrographs showing the expression of 9-O-acetyl GD3 (CD60b in red) and nestin (in green) in the developing cerebral cortex of E14.5 (a–f), P0 (g–i), P7 (j–l), and P21 (m–o) rats. In E14.5, CD60b is expressed in cell bodies and radially oriented structures (a–c) and its distribution is very similar to nestin distribution (d–f). From P0 to P21, there is a progressive decrease in CD60b expression, but its distribution is still similar to nestin distribution. Nuclei were stained with TO-PRO-3 (blue). Scale bars: 50 μm (a–f) and 100 μm (g–o). st: striatum; LV: lateral ventricle.