IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype

<div>Effect of IGF-1 transduction on osteogenic and adipogenic differentiation of human Syn-MSC. (a) Osteogenic differentiation assay using ALP staining after 1 week of differentiation (upper). Alizarin red staining after 3 weeks of differentiation (lower). Scale bars = 500 <i>μ</i>m. (b) Quantitated alizarin red staining values after osteogenic differentiation in the control versus induced IGF-1 groups. (c) Adipogenic differentiation after 3 weeks in a differentiation medium using oil red staining. Scale bars = 100 <i>μ</i>m.</div>

Stem Cells International

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Figure 5

Figure 5: IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype 

Figure 5 | IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype 