Human Mesenchymal Stem/Stromal Cells from Umbilical Cord Blood and Placenta Exhibit Similar Capacities to Promote Expansion of Hematopoietic Progenitor Cells In Vitro

Figure 3

MSCs from UCB and PL increase expansion of the population enriched in CD34⁺CD38⁻Lin⁻ cells. (a) Percent of CD34⁺CD38⁻Lin⁻ cells in cocultures containing cytokines either without MSCs (white bar) or with BM-MSCs (gray bar), UCB-MSCs (black bar), and PL-MSCs (gridded bar). (b) Fold increases in the numbers of CD34⁺CD38⁻Lin⁻ cells in cocultures containing cytokines in the presence of BM-MSCs, UCB-MSCs, and PL-MSCs. Cultures without MSCs and with cytokines were considered controls (without MSCs). Data are shown as the means ± SD for the percent and fold increases in cell number (BM-MSCs: ; UCB-MSCs: ; and PL-MSCs ). indicates a statistically significant difference, .

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