The Flavonoid Glabridin Induces OCT4 to Enhance Osteogenetic Potential in Mesenchymal Stem Cells

<div>Effect of glabridin on stemness and senescence in MSCs. (a) Stemness marker expression in MSCs treated with an increasing concentration of glabridin. (b) Stemness was evaluated by a CFU-F assay. The number of colonies (&gt;50 cells) was counted. (c) <i>P53</i>, <i>P16</i>, and <i>P21</i> mRNA expression levels were analyzed using reverse transcription PCR (RT-PCR). (d) Senescence-associated (SA) <i>β</i>-gal assay. The number of <i>β</i>-gal-positive cells was counted. 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Stem Cells International

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Figure 2

Figure 2: The Flavonoid Glabridin Induces OCT4 to Enhance Osteogenetic Potential in Mesenchymal Stem Cells 