Cardiac Progenitor Cells and the Interplay with Their Microenvironment

Table 1

Summary of the cardiac cell populations described in this review.

Cell type	Cardiac resident		Self-renewal	Multipotent	Activation after injury	Improvement of cardiac function	Defined CPC	[Refs]
	Embryonic	Adult
Side population	+	+	+	+	+	+	Yes	[6, 9, 11, 14, 29–45]
c-kit^+ cells	+	+	+	+	+	+	Yes	[6, 8–12, 35, 46–74]
Sca-1 cells	+	+	+	+	+	+	Yes	[6, 9–13]
Isl1 progenitors	+	?	+	+	?	?	No	[9, 11, 47, 62, 88–99]
Cardiospheres	+	+	+	+	?	?	No	[9, 11, 47, 62, 87, 88]