Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound

<div>Time-lapse live cell images of (a) the DMSO-treated group and (b) the NHPDQC-treated group in pT<i>α</i>1-DsRed2-transfected MSCs. NHPDQC treatment to induce neuronal differentiation showed that the fluorescence signals in MSCs transfected with pT<i>α</i>1-DsRed2 were gradually increased according to cellular phenotypic changes. (c) Neurite growth (gray) and fluorescence signals (black) were increased in the NHPDQC-treated group than the DMSO-treated cell group from 2 h after treatment. Fluorescence signal in the NHPDQC-treated group was dropped at 24 h after treatment. In contrast, neurite growth was progressed at 30 h after treatment.</div>

Stem Cells International

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Figure 5

Figure 5: Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound 

Figure 5 | Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound 