Involvement of WNT Signaling in the Regulation of Gestational Age-Dependent Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation

Figure 2

Gene expression microarray analysis of preterm and term UC-MSCs. (a) PCA mapping of gene expression profile for preterm (pre-1-5) and term (term-1-3) UC-MSCs. (b) Heat map of 5578 differentially expressed gene with greater than twofold changes in preterm UC-MSCs as compared to term UC-MSCs at a corrected value less than 0.05. Green color refers to low levels of gene expression and red color to high levels. (c) Pie chart of altered expression genes and WNT signaling pathway genes. The list shows overlapped 32 genes. (d) Heat map of 32 genes extracted from (c). Green color refers to low levels of gene expression and red color to high levels.

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