Electromagnetic Fields for the Regulation of Neural Stem Cells

Figure 1

The electrophysiological differences between NSCs and neurons. Compared to mature functional neurons, NSCs exhibit a higher RMP and a lower Rin due to shortage of Kir; moreover, it is not easy for NSCs to generate AP because of a lack of VGSCs. VGCCs, mostly functional L-type and LGCC, are probably the main roles in modulating intracellular Ca²⁺ concentration especially L-type VGCCs, Ca²⁺-dependent K⁺ channel SK3 abundantly expressed in NSCs is responsible for the migration and proliferation.