Type III Transforming Growth Factor-<i>β</i> Receptor RNA Interference Enhances Transforming Growth Factor <i>β</i>3-Induced Chondrogenesis Signaling in Human Mesenchymal Stem Cells

<div>T<i>β</i>RIII RNAi strengthened TGF-<i>β</i>3-mediated Smad2/3 phosphorylation. SiNC- or SiT<i>β</i>RIII-infected cells were cultured in control medium (C-SiNC group; C-SiT<i>β</i>RIII group) or chondrogenic medium containing TGF-<i>β</i>3 (T-SiNC group; T-SiT<i>β</i>RIII group) and harvested after 24 h. (a) A Western blot of protein levels of P-Smad2/3, total Smad2/3, and GAPDH. (b) Quantification of protein levels of P-Smad2/3 normalized to total levels of Smad2/3 or GAPDH. 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Stem Cells International

fig5

Figure 5

Figure 5: Type III Transforming Growth Factor-<i>β</i> Receptor RNA Interference Enhances Transforming Growth Factor <i>β</i>3-Induced Chondrogenesis Signaling in Human Mesenchymal Stem Cells 

Figure 5 | Type III Transforming Growth Factor-β Receptor RNA Interference Enhances Transforming Growth Factor β3-Induced Chondrogenesis Signaling in Human Mesenchymal Stem Cells 