Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts’ Recommendations: Choosing Optimal Monitoring Tools

Figure 5

Muscle strength and electrophysiological assessment. The detailed clinical evaluation performed within one week of the neurosurgery procedure and repeated every 3 months throughout the project was complemented with ALS-FRS-R, MRC, MUNIX, and HHD evaluation. ALSFRS R and MRC shared a similar deterioration pattern. The slope of decline was much steeper in the case of both MUNIX and muscle strength as examined by HHD. The MUNIX and HHD showed a marked decline even when the values of ALSFRS R and MRC were still stable ( P1, P2, and P3—resp. patient 1, patient 2, and patient 3).